FY 2024 Alzheimer’s Disease and Related Dementias Bypass Budget Released

At today’s meeting of the Advisory Council on Alzheimer’s Research, Care, and Services, NIA Director Dr. Richard Hodes presented the NIH FY 2024 Professional Judgment Budget, “Looking Forward: Opportunities to Accelerate Alzheimer’s and Related Dementias Research.” For FY 2024, the content and structure of the Professional Judgment Budget, or “Alzheimer’s Disease Bypass Budget” (ADBB), have been updated. Previous ADBB narratives focused on scientific accomplishments in AD/ADRD research. The FY 2024 ADBB narrative outlines examples of prospective research opportunities that could be supported with additional funds in FY 2024. Examples of future research opportunities are organized across six broad scientific categories:

  • Epidemiology/Population Studies
  • Disease Mechanisms
  • Diagnosis, Assessment, & Disease Monitoring
  • Translational Research & Clinical Interventions
  • Dementia Care & Impact of Disease
  • Research Resources

The FY 2024 ADBB also emphasizes significant cross-cutting research efforts centered on health equity and inclusion. For FY 2024, additional NIH resources needed for new Alzheimer’s and related dementias research are $321 million, which would bring the total FY 2024 NIH resource needs for AD/ADRD research to $3.87 billion.

NIA’s Office of Legislation, Policy, and International Activities will hold a webinar for stakeholders on Thursday, August 11th, from 11:00 am—12:00 pm ET to review the FY 2024 ADBB and answer any questions you may have. To register, please visit the webinar registration page.

FY2023 NIH Professional Judgement Budget for Alzheimer’s Disease and Related Dementias

In a recent InsideNIA blog post, NIA Director Dr. Richard Hodes highlighted the newly released FY 2023 NIH Professional Judgment Budget for Alzheimer’s Disease and Related Dementias, also known as the “bypass budget.” The report, titled Transforming Research to Prevent, Detect, Treat, and Provide Better Care for Dementia, features summaries of key studies in Alzheimer’s and related dementias (AD/ADRD) research and the tremendous progress of NIA scientists and grantees in this area. In addition, the FY 2023 bypass budget identifies $226 million in additional resources needed for new AD/ADRD research to help reach the goal of the National Plan to Address Alzheimer’s Disease – to effectively treat and prevent these diseases by 2025.

2021 NIH Alzheimer’s Research Summit: Path to Precision Medicine for Treatment and Prevention

NIH Alzheimer’s Research Summits are key strategic planning meetings tied to the implementation of the first goal of the National Plan to Address Alzheimer’s Disease: to effectively treat and prevent Alzheimer’s disease by 2025. They bring together a multi-stakeholder community including government, industry, academia, private foundation, and patient advocacy groups, to further integrated, translational Alzheimer’s research. The goal is to accelerate the development of effective, disease-modifying, and palliative therapies for the cognitive as well as neuropsychiatric symptoms of Alzheimer’s disease.

The 2021 Summit will be held virtually April 19 – April 22 from 10:00 a.m. – 3:30 p.m. ET.

NIH Videocast, April 19-22, 2021, 10 a.m. – 3:30 p.m. ET. Registration is free and open to the public.

Register Now: Development of an NIA Practice-Based Research Network to Conduct AD/ADRD Clinical Research

The National Institute on Aging will be hosting a virtual meeting to discuss the potential and planning of a practice-based research network (PBRN) to address the disparities gap with the recruitment and retention of diverse and underserved populations to AD/ADRD clinical research studies.

PBRNs are networks of health care clinicians and practices working together to answer community-based health care questions and translate research findings into practice–they have the potential to directly engage diverse and underserved communities in AD/ADRD clinical research.

When: Friday, April 30, 2021; 2:00 – 5:00 p.m. EDT

Keynote Speakers: Lori Minasian, MD, Deputy Director for the National Cancer Institute (NCI) Division of Cancer Prevention and Jonathan N. Tobin, PhD, Cardiovascular Epidemiologist and Professor in the Department of Epidemiology and Population Health at Albert Einstein College of Medicine

Panel Speakers: Jennifer Manly, PhD, Andrea Gilmore-Bykovskyi, PhD, RN, and Jonathan Jackson, PhD

Who Should Attend: Researchers and other stakeholders who are interested in learning about PBRNs to address AD/ADRD research gaps

Click here to register.

NIA-funded Biotech Company May Be One Step Closer to Developing a Blood-Based Diagnostic for Alzheimer’s Disease

An NIA-funded biotech company may be one step closer to developing a blood-based diagnostic for Alzheimer’s disease.  This biotech company, Amprion, recently received a Breakthrough Device Designation by the FDA for a test developed to detect the alpha-synuclein protein in the cerebrospinal fluid and bloodstream, a known biomarker for Parkinson’s disease.  Such designation by the FDA paves the way for faster development, assessment, and review, and potentially FDA approval of the technology.  Small Business grants from the NIA are enabling Amprion to adopt their test to specifically detect traces of two biomarkers for Alzheimer’s disease, amyloid and tau aggregates, in cerebrospinal fluid and the bloodstream.  With this new FDA designation for their technology, this company may be on track to develop a test that could help facilitate early detection and diagnosis of these devasting diseases.